How Technical Information Influences Your Health Choices

Nature's Herbal Medicine

Hi, I'm Mark Vuozzo, the Chief Technical Officer at Purblend Science, Inc. I'm the wizard behind the curtain, bringing you the goodness of our products. Our unique approach and tools ensure we deliver the purest full-spectrum products to market. Technical information can go over a lot of people’s heads without proper understanding.  I have been reading research papers for years which drive our product development.  Honestly, I am always ahead of this curve as we introduce products then studies are later released indicating validation of products, we already know work. Medical marijuana is a complex topic with many moving parts.  It is my job to influence this movement while refining our product offerings.

Many of our clients trust our formulations because they work. As we evolve, I will publish blogs that highlight important technical information in an understandable way. I will summarize key technical details about our nature's medicine and provide links for further investigation.

Lastly, it's important to note that we are limited by FDA guidelines in what we can say about our products' efficacy. For example, we cannot claim to cure cancer, even if clients have experienced remission. We also avoid terms like 'Pain Relief,' which is why we use simple names like ReLiever and Arti Rub. For in-depth conversations, feel free to reach out at info@purblendcbd.com.

Ever wonder why PurBlend’s CBD is different?  Today a study was published that speaks directly to this question. Read below for a summary of this study or click the following link to read the entire article.

https://www.marijuanamoment.net/medical-marijuana-effectively-treats-pain-with-terpenoids-being-more-influential-than-thc-or-cbd-study-shows/

Medical Marijuana Effectively Treats Pain, With Terpenoids Being ‘More Influential’ Than THC or CBD, Study Shows

Medical marijuana has “genuine therapeutic effects for pain management,” and the degree of relief provided by cannabis can be predicted by their specific chemical profile—including not only cannabinoids but also, crucially, terpenoids—according to a newly published study employing machine learning methods.

It’s a conclusion that researchers say provides “evidence for compound-specific therapeutic effects.”

“These results highlight the importance of considering the full range of cannabis compounds when developing more precise and effective cannabis-based therapies for pain management,” says the report, published in the journal Communications Medicine.

Why does full spectrum and purity matter?

It also furthers the notion that at least some combinations of the many compounds in cannabis work in concert to provide heightened relief—a concept known as the entourage effect.

One notable finding in the new research is that primary cannabinoids THC and CBD offered only “limited predictive value” of a product’s pain-relieving effects. Other minor compounds, specifically alpha-Bisabolol and eucalyptol, instead emerged as “key predictors of treatment response.”

“An unexpected finding was the relatively minimal impact of well-known cannabinoids such as THC and CBD on pain relief outcomes, which stands in contrast to popular belief and previous reports,” the study says. “While THC and CBD are often highlighted for their therapeutic potential, our analysis revealed other compounds, including α-Bisabolol and eucalyptol, as more influential in the context of pain relief.”

As for the entourage effect, the report suggests that “specific combinations of compounds” work better at managing pain than individual chemical components.

“These findings show that medical cannabis has genuine therapeutic effects for pain management.”

The paper also said select mixtures of cannabinoids—such as cannabichromene (CBC) and cannabigerol (CBG)—could have other benefits, including minimizing undesirable effects like the psychoactivity of THC.

All told, more than 180 different cannabinoids have now been isolated from the cannabis plant, the report noted, often interacting with different parts of the body. CBD and THC, for example, “have a wide potential for therapeutic effects based on their multiple molecular targets including ion channels, receptors, transporters and enzymes.”

“The two most abundant and studied cannabinoids, THC and CBD, along with an understudied cannabinoid, cannabigerol (CBG), have been shown, in our laboratories, to reduce neuropathic pain in animal models,” authors wrote, recommending that further study “into cannabinoids like THC, CBD and CBG should focus on the optimal therapeutic doses and the effects these cannabinoids can have on the management of chronic neuropathic pain in humans.”

In summary, Purblend Science is very aware of the above information and guarantees that all of the above compounds as available in the strain extracted are in our oils in a super pure format and those oils are in our finished products.

Stay tuned for more technical information.